Search results for "Descemet Membrane"

showing 5 items of 5 documents

Comparison of DMEK and DSAEK in Eyes With Endothelial Decompensation After Previous Penetrating Keratoplasty.

2021

PURPOSE Posterior lamellar keratoplasty is increasingly applied in patients with endothelial decompensation after penetrating keratoplasty (PK). The aim of this study was to compare the results of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) after PK. METHODS In this retrospective study, clinical data of 30 patients who received DMEK (n = 19) or DSAEK (n = 11) for endothelial decompensation after PK were evaluated. All lamellar keratoplasties were performed at the Department of Ophthalmology at University Hospital Mainz, Germany. Primary end point included best-corrected visual acuity, and secondary end points included e…

AdultMalemedicine.medical_specialtyVisual acuityDescemet membraneVisual AcuityCell CountCorneal DiseasesYoung AdultOphthalmologymedicineHumansDecompensationIn patientPostoperative PeriodAgedRetrospective StudiesAged 80 and overGraft rejectionbusiness.industryGraft SurvivalEndothelial CellsCorneal Endothelial Cell LossMiddle AgedUniversity hospitalDescemet stripping automated endothelial keratoplastyEndothelial cell densityOphthalmologyFemalemedicine.symptombusinessDescemet Stripping Endothelial KeratoplastyKeratoplasty PenetratingCornea
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Postoperative Repositioning of Inverted Descemet Membrane Endothelial Keratoplasty Grafts

2019

Item does not contain fulltext PURPOSE: To present 4 cases of postoperative repositioning of inverted grafts after Descemet membrane endothelial keratoplasty (DMEK). METHODS: Retrospective case reports of 4 patients presenting with subtotal to total graft detachment after DMEK, most probably owing to upside-down graft positioning. Graft repositioning was performed 1 to 14 days after initial DMEK surgery. In 3 cases (cases 1, 3, and 4), repositioning was performed without removing the graft from the anterior chamber (AC), whereas for case 2, the graft had to be removed from the AC to attain correct graft orientation. RESULTS: In all 4 cases, the initially upside-down DMEK grafts could be suc…

Graft RejectionMaleReoperationmedicine.medical_specialtyDescemet membraneClear corneasSensory disorders Donders Center for Medical Neuroscience [Radboudumc 12]Corneal Diseases03 medical and health sciences0302 clinical medicinePostoperative ComplicationsCorneal edemaOphthalmologyCorneamedicineHumansDescemet MembraneAgedRetrospective StudiesAged 80 and overbusiness.industryMiddle AgedEndothelial cell densityOphthalmologymedicine.anatomical_structuresurgical procedures operative030221 ophthalmology & optometryFemalebusiness030217 neurology & neurosurgeryDescemet Stripping Endothelial KeratoplastyCornea. the Journal of Cornea and External Disease
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Descemet Membrane Endothelial Keratoplasty for Corneal Decompensation Secondary to Phakic Intraocular Lenses

2019

Purpose. To describe the surgical technique and clinical outcomes of bilensectomy (pIOL explant and phacoemulsification), followed by DMEK performed for bullous keratopathy secondary to pIOL.Methods. Seven eyes of seven patients, who developed corneal decompensation after pIOL implantation, underwent bilensectomy followed by DMEK in a two-step procedure. Main outcome measures included uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), refraction, endothelial cell density (ECD) at 1, 3, 6, and 12 months, and intraoperative and postoperative complications.Results. DMEK was performed at a mean time of 9.83 ± 8.23 months after bilensectomy. BCVA (log MAR) improved in all …

medicine.medical_specialtyVisual acuityDescemet membraneCorneal Decompensationgenetic structuresArticle Subjectbusiness.industrymedicine.medical_treatmentUncorrected visual acuityPhacoemulsificationPhakic intraocular lenseye diseasesOphthalmologylcsh:Ophthalmologylcsh:RE1-994OphthalmologyBullous keratopathymedicinePrimary graft failuremedicine.symptombusinessResearch ArticleJournal of Ophthalmology
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Corneal opacity and copper levels of the Lewis syndrome after systemic chemotherapy

2020

Abstract Purpose To report a female patient of biclonal Lewis syndrome which consists of a trias: biclonal gammopathy of undetermined significance, paraproteinemic keratopathy in form of a brownish discoid opacification at the level of Descemet's membrane and hypercupremia. After several years there was a conversion to multiple myeloma. Systemic chemotherapy led to a complete remission of multiple myeloma and to a normalization of the copper level in the blood that lasted five years. The corneal opacification remained unchanged. Observations A currently 66-year-old woman suffered from biclonal Lewis syndrome. On both eyes there is a central discoid yellow-brownish discoloration in the Pre-D…

medicine.medical_specialtymedicine.medical_treatmentUnchanged corneal opacity after chemotherapyGastroenterology03 medical and health sciences0302 clinical medicinelcsh:OphthalmologyChemotherapy-induced normal level of copper in serumInternal medicineMedicineAffinity of IgG to copper in Lewis syndromeCopper levelsProgressive anemiaMultiple myelomaLewis syndromeHypercupremiaChemotherapyBiclonal gammopathybusiness.industrySystemic chemotherapyHypercupremiaCorneal opacitymedicine.diseaseOphthalmologylcsh:RE1-994030221 ophthalmology & optometrybusinessDiscoid brownish opacification of Descemet membrane030217 neurology & neurosurgeryAmerican Journal of Ophthalmology Case Reports
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Structural, ultrastructural, and morphometric study of the zebrafish ocular surface: a model for human corneal diseases?

2018

Purpose: A morphological and morphometric study of the adult zebrafish ocular surface was performed to provide a comprehensive description of its parts and to evaluate its similarity to the human. Materials and Methods: The eyes of adult zebrafish were processed for light, transmission and scanning electron microscopy, and for immunohistochemical stain of corneal nerves; a morphometric analysis was also performed on several morphological parameters. Results: The corneal epithelium was formed by five layers of cells. No Bowman’s layer could be demonstrated. The stroma consisted of lamellae of different thickness with few keratocytes. The Descemet’s membrane was absent as the flat and polygon…

0301 basic medicineBowman's layer; corneal nerves; Descemet's membrane; ocular surface; Zebrafish; Ophthalmology; Sensory Systems; Cellular and Molecular NeuroscienceConjunctivaCorneal StromaBiologycorneal nerveCorneal DiseasesCornea03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineMicroscopy Electron TransmissionCorneamedicineAnimalsHumansTrigeminal NerveBowman MembraneZebrafishDescemet MembraneZebrafishTrigeminal nerveocular surfaceBowman’s layerCorneal DiseasesEndothelium CornealEpithelium CornealDescemet’s membraneEpithelial CellsAnatomybiology.organism_classificationSensory SystemsDescemet's membraneOphthalmology030104 developmental biologymedicine.anatomical_structureModels Animal030221 ophthalmology & optometryUltrastructureMicroscopy Electron ScanningGoblet CellsBowman MembraneConjunctivaCurrent eye research
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